Droplet-based microfluidic synthesis of nanogels for controlled drug delivery: tailoring nanomaterial properties <i>via</i> pneumatically actuated flow-focusing junction-Reference-Cited by-同舟云学术

Droplet-based microfluidic synthesis of nanogels for controlled drug delivery: tailoring nanomaterial properties via pneumatically actuated flow-focusing junction

Published:2022 Issue:31 Volume:14 Page:11415-11428
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Giannitelli Sara Maria¹^ORCID,Limiti Emanuele¹^ORCID,Mozetic Pamela²³^ORCID,Pinelli Filippo⁴,Han Xiaoyu⁵,Abbruzzese Franca¹,Basoli Francesco¹,Del Rio Danila⁶,Scialla Stefano¹⁷^ORCID,Rossi Filippo⁴^ORCID,Trombetta Marcella¹,Rosanò Laura⁶^ORCID,Gigli Giuseppe³⁸,Zhang Zhenyu Jason⁵^ORCID,Mauri Emanuele¹^ORCID,Rainer Alberto¹³^ORCID

Affiliation:

1. Department of Engineering, Università Campus Bio-Medico di Roma, via Álvaro del Portillo 21, 00128 Rome, Italy

2. Division of Neuroscience, Institute of Experimental Neurology, San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy

3. Institute of Nanotechnology (NANOTEC), National Research Council, via Monteroni, 73100, Lecce, Italy

4. Department of Chemistry, Materials and Chemical Engineering “G. Natta”, Politecnico di Milano, via L. Mancinelli 7, 20131 Milan, Italy

5. School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

6. Institute of Molecular Biology and Pathology, National Research Council (CNR), via Degli Apuli 4, 00185 Rome, Italy

7. National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618 Tallinn, Estonia

8. Department of Mathematics and Physics “Ennio De Giorgi”, Università del Salento, via per Arnesano, 73100 Lecce, Italy

Abstract

A droplet-based microfluidic process relying on an actuated flow-focusing device was used for the in-flow synthesis of hyaluronic acid-polyethyleneimine nanogels with improved drug delivery properties.

Funder

Ministero dell'Istruzione, dell'Università e della Ricerca

Regione Lazio

Regione Puglia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR00827K

Reference77 articles.

1. Recent developments in functionalized polymer nanoparticles for efficient drug delivery system