Enhancement of nucleic acid delivery to hard-to-transfect human colorectal cancer cells by magnetofection at laminin coated substrates and promotion of the endosomal/lysosomal escape-Reference-Cited by-同舟云学术

Enhancement of nucleic acid delivery to hard-to-transfect human colorectal cancer cells by magnetofection at laminin coated substrates and promotion of the endosomal/lysosomal escape

Published:2015 Issue:72 Volume:5 Page:58345-58354
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cerda María Belén¹²³⁴⁵,Batalla Milena¹²³⁴⁶,Anton Martina⁷⁸⁹¹⁰,Cafferata Eduardo⁵⁴¹¹¹²¹³,Podhajcer Osvaldo⁵⁴¹¹¹²¹³,Plank Christian⁷⁸⁹¹⁰,Mykhaylyk Olga⁷⁸⁹¹⁰,Policastro Lucia¹²³⁴⁵

Affiliation:

1. Laboratory of Nanomedicine

2. National Atomic Energy Commission

3. Buenos Aires

4. Argentina

5. Consejo Nacional Investigación Científicas y Técnicas (CONICET)

6. Institute of Nanoscience and Nanotechnology

7. Institute of Experimental Oncology and Therapy Research

8. Technische Universität München

9. Munich

10. Germany

11. Laboratory of Molecular and Cellular Therapy

12. Leloir Institute Foundation

13. Ciudad Autónoma de Buenos Aires

Abstract

Optimization of nucleic acid delivery in hard-to-transfect colorectal cancer cells by magnetofection at coated laminin substrates and by the endosomal escape enhancement of magnetic complexes using INF-7 peptide.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06562C

Reference49 articles.

1. Viral and nonviral delivery systems for gene delivery

2. Transfecting the hard-to-transfect lymphoma/leukemia cells using a simple cationic polymer nanocomplex

3. Improved Tat-mediated plasmid DNA transfer by fusion to LK15 peptide

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