Chemical diversity and mode of action of natural products targeting lipids in the eukaryotic cell membrane-Reference-Cited by-同舟云学术

Chemical diversity and mode of action of natural products targeting lipids in the eukaryotic cell membrane

Published:2020 Issue:5 Volume:37 Page:677-702
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Nishimura Shinichi¹²³⁴⁵^ORCID,Matsumori Nobuaki⁶⁷⁸⁵^ORCID

Affiliation:

1. Department of Biotechnology

2. Collaborative Research Institute for Innovative Microbiology

3. The University of Tokyo

4. Tokyo 113-8657

5. Japan

6. Department of Chemistry

7. Kyushu University

8. Fukuoka 819–0395

Abstract

This review article focuses on natural products that bind to eukaryotic membrane lipids, and includes clinically important molecules and key research tools. How their mechanism was unveiled, and how they are used in research are also mentioned.

Funder

Exploratory Research for Advanced Technology

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Institute for Fermentation, Osaka

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NP/C9NP00059C

Reference251 articles.

1. Property Distributions: Differences between Drugs, Natural Products, and Molecules from Combinatorial Chemistry

2. Natural Products as Sources of New Drugs from 1981 to 2014

3. Natural Products as Chemical Probes

4. Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds

5. Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

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