A lipophilic AIEgen for lipid droplet imaging and evaluation of the efficacy of HIF-1 targeting drugs-Reference-Cited by-同舟云学术

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A lipophilic AIEgen for lipid droplet imaging and evaluation of the efficacy of HIF-1 targeting drugs

Published:2020 Issue:7 Volume:8 Page:1516-1523
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Shi Xiujuan¹²³⁴⁵^ORCID,Sung Simon H. P.¹²³⁴⁵,Lee Michelle M. S.⁴⁵⁶⁷⁸,Kwok Ryan T. K.¹²³⁴⁵,Sung Herman H. Y.⁴⁵⁶⁷⁸,Liu Haixiang¹²³⁴⁵,Lam Jacky W. Y.¹²³⁴⁵,Williams Ian D.⁴⁵⁶⁷⁸^ORCID,Liu Bin⁹¹⁰¹¹^ORCID,Tang Ben Zhong¹²³⁴⁵^ORCID

Affiliation:

1. HKUST Shenzhen Research Institute

2. Shenzhen 518057

3. China

4. Department of Chemistry

5. Department of Chemical and Biological Engineering

6. Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, and Institute of Advanced Study

7. The Hong Kong University of Science and Technology

8. Kowloon

9. Department of Chemical and Biomolecular Engineering

10. National University of Singapore

11. Singapore

Abstract

A lipid-droplet-specific AIEgen was used to evaluate the inhibitory efficacy of HIF-1-targeting drugs by assessing lipid-droplet levels.

Funder

National Natural Science Foundation of China

University Grants Committee

Research Grants Council, University Grants Committee

Innovation and Technology Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/C9TB02848J

Reference72 articles.

1. The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy

2. Hallmarks of Cancer: The Next Generation

3. Hypoxia after stroke: a review of experimental and clinical evidence

4. Oxygen, oxidative stress, hypoxia, and heart failure

5. Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism

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