Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery

Author:

Sun Yao12345,Ding Mingmin12345,Zeng Xiaodong12345,Xiao Yuling12345,Wu Huaping12345,Zhou Hui12345,Ding Bingbing12345,Qu Chunrong12345,Hou Wei12345,Er-bu AGA6789,Zhang Yejun10119,Cheng Zhen1213141516,Hong Xuechuan12345ORCID

Affiliation:

1. State Key Laboratory of Virology

2. Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE)

3. Hubei Provincial Key Laboratory of Developmentally Originated Disease

4. Wuhan University School of Pharmaceutical Sciences

5. Wuhan 430071

6. Medical College

7. Tibet University

8. Lasa

9. China

10. Suzhou NIR-Optics Technologies Co., Ltd

11. Suzhou

12. Molecular Imaging Program at Stanford (MIPS)

13. Bio-X Program

14. Department of Radiology

15. Stanford University

16. California 94305-5344

Abstract

This work presents the establishment of novel bright-emission small-molecule NIR-II fluorophores forin vivotumor imaging and NIR-II image-guided sentinel lymph node surgery.

Funder

National Natural Science Foundation of China

National Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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