Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL

Published:2017 Issue:37 Volume:15 Page:7956-7976
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kellici Tahsin F.¹²³⁴¹^ORCID,Chatziathanasiadou Maria V.¹²³⁴^ORCID,Lee Min-Sung⁵⁶⁷⁸,Sayyad Nisar¹²³⁴,Geromichalou Elena G.⁹¹⁰¹¹⁴,Vrettos Eirinaios I.¹²³⁴^ORCID,Tsiailanis Antonis D.¹²³⁴,Chi Seung-Wook⁵⁶⁷⁸,Geromichalos George D.¹²¹³¹⁴¹⁵⁴,Mavromoustakos Thomas¹¹⁶⁴^ORCID,Tzakos Andreas G.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Ioannina

3. Ioannina 45110

4. Greece

5. Disease Target Structure Research Center

6. KRIBB

7. Daejeon 34141

8. Republic of Korea

9. Laboratory of Pharmacology

10. Medical School National and Kapodistrian University of Athens

11. Athens 11527

12. Laboratory of Inorganic Chemistry

13. Faculty of Chemistry

14. Aristotle University of Thessaloniki

15. GR-54124 Thessaloniki

16. National and Kapodistrian University of Athens

Abstract

Anti-apoptotic proteins, like the Bcl-2 family proteins, present an important therapeutic cancer drug target.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02045G

Reference66 articles.

1. The BCL-2 protein family: opposing activities that mediate cell death

2. Bcl-2 family members: Dual regulators of apoptosis and autophagy

3. The role of Bcl-2 family members in tumorigenesis

4. Structural biology of the Bcl-2 family of proteins

5. Bcl-2 family proteins and cancer

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The nephroprotective effect of Quercetin in Cyclophosphamide-induced renal toxicity might be associated with MAPK/ERK and NF-κB signal modulation activity;Drug and Chemical Toxicology;2024-05-10

2. Quercetin: A Potential Polydynamic Drug;Molecules;2023-12-17

3. Research Progress on Quercetin's Biological Activity and Structural Modification Based on Its Antitumor Effects;ChemistrySelect;2023-11-05

4. Drug design strategies that aim to improve the low solubility and poor bioavailability conundrum in quercetin derivatives;Expert Opinion on Drug Discovery;2023-07-29

5. Development of a Novel Apigenin Dosage form as a Substitute for the Modern Triple Antithrombotic Regimen;Molecules;2023-03-02

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3