Cornulacin: a new isoflavone from <i>Cornulaca monacantha</i> and its isolation, structure elucidation and cytotoxicity through EGFR-mediated apoptosis-Reference-Cited by-同舟云学术

Cornulacin: a new isoflavone from Cornulaca monacantha and its isolation, structure elucidation and cytotoxicity through EGFR-mediated apoptosis

Published:2024 Issue: Volume: Page:
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Badawy Ahmed M.¹^ORCID,Eltamany Enas E.²^ORCID,Hussien Rodina M.¹,Mohamed Osama G.³⁴^ORCID,El-Ayouty Mayada M.¹^ORCID,Nafie Mohamed S.⁵⁶^ORCID,Tripathi Ashootosh⁴⁷^ORCID,Ahmed Safwat A.²

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, Sinai University – Arish Branch, Arish, 45511, Egypt

2. Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

3. Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini St., Cairo 11562, Egypt

4. Natural Products Discovery Core, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA

5. Department of Chemistry, College of Sciences, University of Sharjah, P. O. Box 27272, Sharjah, United Arab Emirates

6. Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt

7. Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA

Abstract

Cornulacin, a new isoflavone, was isolated from Cornulaca monacantha with structural elucidation and cytotoxicity against ovarian A2780 cancer through apoptosis induction.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00524D

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