Efficient hydration of 2-amino-2,3-dimethylbutyronitrile to 2-amino-2,3-dimethylbutyramide in a biphasic system via an easily prepared whole-cell biocatalyst

Author:

Zhu Shujing12345,Ma Xiaoqiang12345,Su Erzheng67895,Wei Dongzhi12345

Affiliation:

1. State Key Laboratory of Bioreactor Engineering

2. New World Institute of Biotechnology

3. East China University of Science and Technology

4. Shanghai 200237

5. China

6. Enzyme and Fermentation Technology Laboratory

7. College of Light Industry Science and Engineering

8. Nanjing Forestry University

9. Nanjing 210037

Abstract

The nitrile hydratase catalyzed hydration of 2-amino-2,3-dimethylbutyronitrile to 2-amino-2,3-dimethylbutyramide in various green solvent–aqueous reaction systems was investigated in this study.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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5. M. P. C. Marques , N. M. T.Lourenço, P.Fernandes and C. C. C. R.de Carvalho, Green Solvents I: Properties and Applications in Chemistry, Green Solvents for Biocatalysis, Springer, Netherlands, Berlin, 2012, pp. 121–146

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