5′-Vitamin B12 derivatives suitable for bioconjugation via the amide bond-Reference-Cited by-同舟云学术

5′-Vitamin B12 derivatives suitable for bioconjugation via the amide bond

Published:2018 Issue:6 Volume:16 Page:936-943
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Jackowska A.¹²³,Chromiński M.¹²³,Giedyk M.¹²³,Gryko D.¹²³^ORCID

Affiliation:

1. Institute of Organic Chemistry Polish Academy of Sciences

2. 01-224 Warsaw

3. Poland

Abstract

Vitamin B₁₂ derivatives bearing either the amino or the carboxylic group at the 5′-position were synthesised hence enabling conjugation of therapeutics to vitamin B₁₂via the amide bond.

Funder

Narodowe Centrum Nauki

Fundacja na rzecz Nauki Polskiej

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02898A

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5. Structural Basis for Universal Corrinoid Recognition by the Cobalamin Transport Protein Haptocorrin

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