A highly sensitive method for quantification of iohexol

Author:

Schulz Anna123,Boeringer Falko123,Swifka Janine456,Kretschmer Axel456,Schaefer Mandy123,Jankowski Vera12378,van der Giet Markus123,Schuchardt Mirjam123,Toelle Markus123,Tepel Martin91011,Schlieper George71213,Zidek Walter123,Jankowski Joachim12378

Affiliation:

1. Charité-Universitätsmedizin Berlin (CBF)

2. Medizinische Klinik IV

3. D-12200 Berlin, Germany

4. Bayer Pharma AG

5. Global Drug Discovery – Clinical Sciences

6. Wuppertal, Germany

7. Universitätsklinikum RWTH Aachen

8. Institute for Molecular Cardiovascular Research (IMCAR)

9. University of Southern Denmark

10. Institute of Molecular Medicine

11. Odense, Denmark

12. Medizinische Klinik II

13. Aachen, Germany

Abstract

Iohexol (1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl) acetamide-2,4,6-triiodobenzene-1,3-dicarboxamide) is used for accurate determination of the glomerular filtration rate (GFR) in chronic kidney disease (CKD) patients.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference28 articles.

1. Chronic kidney disease as a global public health problem: Approaches and initiatives – a position statement from Kidney Disease Improving Global Outcomes

2. USRD 2006 ADR/reference tables: http://www.usrds.org/reference_2006.htm

3. Detection of Chronic Kidney Disease With Creatinine, Cystatin C, and Urine Albumin-to-Creatinine Ratio and Association With Progression to End-Stage Renal Disease and Mortality

4. J. Hernandez Ocampo , A.Torres Rosales and F.Rodriguez Castellanos , Nefrologia: publicacion oficial de la Sociedad Espanola Nefrologia , 2010 , vol. 30 , pp. 324–330

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