Transient protein encounters characterized by paramagnetic NMR
Author:
Affiliation:
1. Jean Jeener NMR Centre
2. Structural Biology Brussels
3. Vrije Universiteit Brussel
4. 1050 Brussels, Belgium
5. Molecular Recognition Unit
Abstract
Multiple encounters, sampled by interacting proteins in search of the dominant, functionally active orientation, are visualized by paramagnetic NMR.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/SC/C4SC01232A
Reference39 articles.
1. G. Adam and M.Delbruck, in Structural Chemistry and Molecular Biology, ed. A. Rich and N. Davidson, Freeman, San Francisco, 1968, pp. 198–215
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3. Exploring sparsely populated states of macromolecules by diamagnetic and paramagnetic NMR relaxation
4. Detecting transient intermediates in macromolecular binding by paramagnetic NMR
5. Visualization of transient encounter complexes in protein–protein association
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