Experimental and DFT studies of sulfadiazine ‘piano-stool’ Ru(ii) and Rh(iii) complexes
Author:
Affiliation:
1. Department of Chemistry
2. Faculty of Science
3. Cairo University
4. Giza
5. Egypt
6. Institut für Anorganische Chemie
7. Julius-Maximilians-Universität Würzburg
8. D-97074 Würzburg
9. Germany
Abstract
Binding of certain metal complexes to proteins may cause cytotoxicity. While [(η6-p-Cym)Ru(LSZ)2] decomposed during the reaction with hen white egg lysozyme, a Rh(iii) analogue was covalently bio-conjugatedviathe elimination of a sulfadiazine.
Funder
Wellcome Trust
University of Queensland
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA01085E
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