Succinylated heparin monolayer coating vastly increases superparamagnetic iron oxide nanoparticle T2 proton relaxivity-Reference-Cited by-同舟云学术

Succinylated heparin monolayer coating vastly increases superparamagnetic iron oxide nanoparticle T2 proton relaxivity

Published:2019 Issue:27 Volume:11 Page:12905-12914
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Xie Manman¹²³⁴⁵,Liu Shijia¹²³⁴⁵,Butch Christopher J.¹²³⁴⁵,Liu Shaowei⁶⁷⁸,Wang Ziyang¹²³⁴⁵,Wang Jianquan¹²³⁴⁵,Zhang Xudong¹²³⁴⁵,Nie Shuming¹²³⁴⁵^ORCID,Lu Qian¹²³⁴⁵,Wang Yiqing¹²³⁴⁵^ORCID

Affiliation:

1. Department of Biomedical Engineering

2. College of Engineering and Applied Sciences

3. Nanjing National Laboratory of Microstructures

4. Jiangsu Key Laboratory of Artificial Functional Materials

5. Nanjing University

6. Affiliated Hospital of Nanjing University of Chinese Medicine

7. Nanjing 210029

8. China

Abstract

Superparamagnetic iron oxide nanoparticles (SPIONs) have a history of clinical use as contrast agents in T₂ weighted MRI, though relatively low T₂ relaxivity has caused them to fall out of favor as new faster MRI techniques have gained prominence.

Funder

State Administration for Science, Technology and Industry for National Defense

Jiangsu Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NR/C9NR03965A

Reference49 articles.

1. Magnetic Nanoparticle Facilitated Drug Delivery for Cancer Therapy with Targeted and Image-Guided Approaches

2. Relaxometric and Magnetic Characterization of Ultrasmall Iron Oxide Nanoparticles with High Magnetization. Evaluation as Potential T1 Magnetic Resonance Imaging Contrast Agents for Molecular Imaging