An efficient and practical approach for the synthesis of indoloquinolines and indolo/pyrroloquinoxalines <i>via</i> a Cu-catalyzed Ugi-C/Ugi-<i>N</i>-arylation sequence-Reference-Cited by-同舟云学术

An efficient and practical approach for the synthesis of indoloquinolines and indolo/pyrroloquinoxalines via a Cu-catalyzed Ugi-C/Ugi-N-arylation sequence

Published:2024 Issue:26 Volume:14 Page:18271-18276
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Iranfar Sheiva¹,Shiri Morteza¹^ORCID,Nosood Yazdanbakhsh Lotfi²,Keley Zahra Akbari¹,Tanbakouchian Zahra¹,Amini Zahra¹,Al-Harrasi Ahmed²,Hussain Faiq H. S.³^ORCID

Affiliation:

1. Department of Organic Chemistry, Faculty of Chemistry, Alzahra University, Vanak, Tehran, 1993893973, Iran

2. Natural and Medical Sciences Research Center, University of Nizwa, P. O. Box 33, Birkat Al Mauz, Postal Code 616, Nizwa, Oman

3. Medical Analysis Department, Applied Science Faculty, Tishk International University, Erbil, Kurdistan Region, Iraq

Abstract

A Cu-catalyzed tandem transformation of Ugi adducts through CH/NH bond functionalization reactions was reported for synthesizing a broad spectrum of indolo/pyrrolo-[1,2-a]quinoxaline and indolo[2,3-c]quinoline derivatives in good to excellent yields.

Funder

Al Zahra University

Iran National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA03248A

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