Theranostic nanoparticles enabling the release of phosphorylated gemcitabine for advanced pancreatic cancer therapy

Author:

Wang Qingbing12345,Zhu Xingjun67895,Wu Zhiyuan12345,Sun Tao1011121314,Huang Wei12345,Wang Zhongmin12345,Ding Xiaoyi12345,Jiang Chen1011121314ORCID,Li Fuyou67895ORCID

Affiliation:

1. Department of Interventional Radiology

2. Ruijin Hospital

3. Shanghai Jiao Tong University School of Medicine

4. Shanghai 200025

5. China

6. Institute of Biomedical Sciences

7. Department of Chemistry

8. Fudan University

9. Shanghai 200433

10. Key Laboratory of Smart Drug Delivery

11. Ministry of Education

12. State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science

13. Department of Pharmaceutics

14. School of Pharmacy

Abstract

A lanthanide-based visualizable photothermal controlled drug release nanosystem was developed to overcome the drug resistance of gemcitabine for pancreatic cancer.

Funder

Shanghai Municipal Health Bureau

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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