Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant Staphylococcus aureus-Reference-Cited by-同舟云学术

Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant Staphylococcus aureus

Published:2018 Issue:9 Volume:9 Page:1529-1537
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Li Di¹²³⁴⁵,Bheemanaboina Rammohan R. Yadav¹²³⁴⁵,Battini Narsaiah¹²³⁴⁵,Tangadanchu Vijai Kumar Reddy¹²³⁴⁵,Fang Xian-Fu¹²³⁴⁵,Zhou Cheng-He¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Bioorganic & Medicinal Chemistry

2. Key Laboratory of Applied Chemistry of Chongqing Municipality

3. School of Chemistry and Chemical Engineering

4. Southwest University

5. Chongqing 400715

Abstract

Molecular modeling of organophosphorus aminopyrimidine and the possible antibacterial mechanism.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

State Administration of Foreign Experts Affairs, China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00301G

Reference66 articles.

1. A new class of synthetic retinoid antibiotics effective against bacterial persisters

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