Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories-Reference-Cited by-同舟云学术

Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories

Published:2017 Issue:1 Volume:8 Page:21-52
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Martin Anthony R.¹²³⁴^ORCID,Ronco Cyril¹²³⁴,Demange Luc¹²³⁴⁵,Benhida Rachid¹²³⁴

Affiliation:

1. Université Côte d'Azur

2. CNRS

3. Institut de Chimie de Nice UMR 7272 - 06108 Nice

4. France

5. UFR des Sciences Pharmaceutiques

Abstract

In cancers, hypoxia inducible factor 1 (HIF-1) is an over-expressed transcription factor, which regulates a large set of genes involved in tumour vascularization, metastases, and cancer stem cells (CSCs) formation and self-renewal.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C6MD00432F

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5. Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells

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