Dilute lattice doping of <sup>64</sup>Cu into 2D-nanoplates: its impact on radio-labeling efficiency and stability for target selective PET imaging-Reference-Cited by-同舟云学术

Dilute lattice doping of ⁶⁴Cu into 2D-nanoplates: its impact on radio-labeling efficiency and stability for target selective PET imaging

Published:2022 Issue:45 Volume:10 Page:9389-9399
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Eom Sairan¹²,Kim Min Hwan²,Yoo Ranji²,Choi Goeun³⁴⁵^ORCID,Kang Joo Hyun²,Lee Yong Jin²^ORCID,Choy Jin-Ho³⁶⁷^ORCID

Affiliation:

1. Center for Intelligent Nano-Bio Materials (CINBM), Department of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea

2. Division of Applied-RI, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Republic of Korea

3. Intelligent Nanohybrid Materials Laboratory (INML), Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, Republic of Korea

4. College of Science and Technology, Dankook University, Cheonan 31116, Republic of Korea

5. Department of Nanobiomedical Science and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, Republic of Korea

6. Department of Pre-medical Course, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea

7. International Research Frontier Initiative (IRFI), Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan

Abstract

The designed 64Cu-QT-NPs, where 64Cu radioisotopes were isomorphically doped in the octahedral site of the QT lattice, were showed high labeling efficiency and stability, and selectively targeted to the tumor tissue due to the passive targeting effect.

Funder

National Research Foundation of Korea

Korea Institute of Radiological and Medical Sciences

Ministry of Science and ICT, South Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB01165D

Reference64 articles.

1. Endogenous tumor microenvironment-responsive multifunctional nanoplatforms for precision cancer theranostics

2. Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

3. Recent progress in engineering near-infrared persistent luminescence nanoprobes for time-resolved biosensing/bioimaging

4. Challenges in molecular diagnostic research in cancer nanotechnology

5. Construction of iron oxide nanoparticle-based hybrid platforms for tumor imaging and therapy

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