Novel derivatives of eugenol as potent anti-inflammatory agents <i>via</i> PPARγ agonism: rational design, synthesis, analysis, PPARγ protein binding assay and computational studies-Reference-Cited by-同舟云学术

Novel derivatives of eugenol as potent anti-inflammatory agents via PPARγ agonism: rational design, synthesis, analysis, PPARγ protein binding assay and computational studies

Published:2022 Issue:26 Volume:12 Page:16966-16978
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Anjum Noor Fathima¹,Shanmugarajan Dhivya²³,Shivaraju Vasanth Kumar⁴,Faizan Syed²³,Naishima Namburu Lalitha²³,Prashantha Kumar B. R.²³^ORCID,Javid Saleem¹³,Purohit Madhusudan N.²³^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Farooqia College of Pharmacy, Mysuru 570 015, India

2. Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru 570 015, India

3. JSS Academy of Higher Education & Research, Mysuru 570 015, India

4. DOS in Chemistry, Karnataka State Open University, Mukthagangothri, Mysuru 570 006, India

Abstract

Rational design, synthesis, analysis, PPARγ protein binding assay and computational studies of novel eugenol derivatives.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02116A

Reference38 articles.

1. Self-regulation of the inflammatory response by peroxisome proliferator-activated receptors

2. PPAR-α as a Key Nutritional and Environmental Sensor for Metabolic Adaptation

3. Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases

4. An Overview on the Anti-inflammatory Potential and Antioxidant Profile of Eugenol

5. Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice

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