Simultaneous measurement of contractile force and field potential of dynamically beating human iPS cell-derived cardiac cell sheet-tissue with flexible electronics-Reference-Cited by-同舟云学术

Simultaneous measurement of contractile force and field potential of dynamically beating human iPS cell-derived cardiac cell sheet-tissue with flexible electronics

Published:2021 Issue:20 Volume:21 Page:3899-3909
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ohya Takashi¹²,Ohtomo Haruki¹,Kikuchi Tetsutaro³,Sasaki Daisuke³,Kawamura Yohei²⁴,Matsuura Katsuhisa³,Shimizu Tatsuya³,Fukuda Kenjiro²^ORCID,Someya Takao²⁵^ORCID,Umezu Shinjiro¹^ORCID

Affiliation:

1. Department of Modern Mechanical Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan

2. Thin-Film Device Laboratory & Center for Emergent Matter Science, RIKEN, 2-1, Hirosawa, Wako, Saitama 351-0198, Japan

3. Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku-Ku, Tokyo 162-8666, Japan

4. Department of Integrative Bioscience and Biomedical Engineering, TWIns, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan

5. Electrical and Electronic Engineering and Information Systems, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

Abstract

We show a novel simultaneous measurement system for contractile force and field potential of hiPSC cardiac cell sheet-tissues using flexible electronics. This system will contribute to gaining new insight in pharmacological study of human heart.

Funder

Japan Society for the Promotion of Science

Telecommunications Advancement Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D1LC00411E

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1. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

2. Induced pluripotent stem cells: the new patient?