1,1′-Binaphthyl-2,2′-diol/quinoline (BINOL/QUN) and 1,1′-binaphthyl-2,2′-diol/isoquinoline (BINOL/ISOQUN) adducts were successfully synthesized. Isothermal titration calorimetry (ITC) involving 1,1′-binaphthyl-2,2′-diol (BINOL) and isoquinoline confirming interaction.