Aminolevulinic acid dendrimers in photodynamic treatment of cancer and atheromatous disease-Reference-Cited by-同舟云学术

Aminolevulinic acid dendrimers in photodynamic treatment of cancer and atheromatous disease

Published:2015 Issue:9 Volume:14 Page:1617-1627
ISSN:1474-905X
Container-title:Photochemical & Photobiological Sciences
language:en
Short-container-title:Photochem. Photobiol. Sci.

Author:

Rodriguez L.¹²³,Vallecorsa P.¹²³,Battah S.⁴⁵⁶⁷⁸,Di Venosa G.¹²³,Calvo G.¹²³,Mamone L.¹²³,Sáenz D.¹²³,Gonzalez M. C.⁹¹⁰¹¹³,Batlle A.¹²³,MacRobert A. J.⁸¹²¹³⁷,Casas A.¹²³

Affiliation:

1. Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP). CONICET-Htal de Clínicas Gral. José de San Martín

2. Ciudad de Buenos Aires

3. Argentina

4. School of Biological Sciences

5. University of Essex

6. Wivenhoe Park CO4 3SQ

7. UK

8. Division of Surgery and Interventional Sciences and UCL Institute of Biomedical Engineering

9. Facultad de Ciencias Médicas

10. Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP)

11. CONICET-UNLP

12. University College London

13. London W1W 7EJ

Abstract

ALA dendrimers are taken up by caveolae-mediated endocytosis in macrophages. Intracellular ALA release gives rise to PpIX synthesis and subsequent photosensitization of key cells in atheromas and tumour diseases.

Funder

Biotechnology and Biological Sciences Research Council

Consejo Nacional de Investigaciones Científicas y Técnicas

Agencia Nacional de Promoción Científica y Tecnológica

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/PP/C5PP00126A

Reference54 articles.

1. Photodynamic therapy with endogenous protoporphyrin