Bone remodeling-inspired dual delivery electrospun nanofibers for promoting bone regeneration

Author:

Wang Yi12345,Cui Wenguo678910ORCID,Zhao Xin1112135,Wen Shizhu12345,Sun Yulong12345ORCID,Han Jianmin141516175,Zhang Hongyu12345ORCID

Affiliation:

1. State Key Laboratory of Tribology

2. Department of Mechanical Engineering

3. Tsinghua University

4. Beijing 100084

5. China

6. Shanghai Institute of Traumatology and Orthopaedics

7. Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases

8. Ruijin Hospital

9. Shanghai Jiao Tong University School of Medicine

10. Shanghai 200025

11. Department of Biomedical Engineering

12. The Hong Kong Polytechnic University

13. Hung Hom

14. Department of Dental Materials

15. National Engineering Laboratory for Digital and Material Technology of Stomatology

16. Peking University School and Hospital of Stomatology

17. Beijing 100081

Abstract

We accelerated bone regeneration by 3-fold through bone remodeling-inspired electrospun nanofibers with dual delivery of ALN and silicate.

Funder

National Natural Science Foundation of China

Tsinghua University

State Key Laboratory of Tribology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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