Sambucus nigra flower and berry extracts for food and therapeutic applications: effect of gastrointestinal digestion on in vitro and in vivo bioactivity and toxicity

Author:

Ferreira-Santos Pedro12ORCID,Nogueira António12ORCID,Rocha Cristina M. R.12,Wilson Cristina Pereira12,Teixeira José A.12,Botelho Cláudia12ORCID

Affiliation:

1. CEB – Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal

2. LABBELS—Associate Laboratory, 4710-057-122 Braga, Portugal

Abstract

The digestion of S. nigra extracts influences the stability of its phenolic compounds, although they are able to exert their bioactivity. Non-digested and digested extracts have low toxicity and differentiated activity in normal and cancerous cells.

Funder

European Regional Development Fund

H2020 Marie Skłodowska-Curie Actions

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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