Bacteriophage-based particles carrying the TNF-related apoptosis-inducing ligand (TRAIL) gene for targeted delivery in hepatocellular carcinoma-Reference-Cited by-同舟云学术

Bacteriophage-based particles carrying the TNF-related apoptosis-inducing ligand (TRAIL) gene for targeted delivery in hepatocellular carcinoma

Published:2024 Issue:13 Volume:16 Page:6603-6617
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Sittiju Pattaralawan¹²^ORCID,Wudtiwai Benjawan¹,Chongchai Aitthiphon¹,Hajitou Amin²,Kongtawelert Prachya¹,Pothacharoen Peraphan¹,Suwan Keittisak²^ORCID

Affiliation:

1. Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

2. Cancer Phage Therapy Group, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK

Abstract

The TRAIL (Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand) is a promising candidate for cancer treatment due to its unique ability to selectively induce programmed cell death, or apoptosis, in cancer cells while sparing healthy ones.

Funder

Royal Golden Jubilee (RGJ) Ph.D. Programme

Medical Research Council

CHILDREN with CANCER UK

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR05660K

Reference59 articles.

1. Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries

3. Getting TRAIL back on track for cancer therapy

4. Phase I Dose-Escalation Study of Recombinant Human Apo2L/TRAIL, a Dual Proapoptotic Receptor Agonist, in Patients With Advanced Cancer

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