From A<sup>3</sup>/KA<sup>2</sup> to AYA/KYA multicomponent coupling reactions with terminal ynamides as alkyne surrogates – a direct, green route to γ-amino-ynamides-Reference-Cited by-同舟云学术

From A³/KA² to AYA/KYA multicomponent coupling reactions with terminal ynamides as alkyne surrogates – a direct, green route to γ-amino-ynamides

Published:2022 Issue:17 Volume:24 Page:6467-6475
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Schlimpen Fabian¹^ORCID,Ast Tun¹,Bénéteau Valérie¹,Pale Patrick¹^ORCID,Chassaing Stefan¹^ORCID

Affiliation:

1. Laboratoire de Synthèse, Réactivité Organiques et Catalyse (LASYROC), Institut de Chimie, CNRS-UMR7177, Université de Strasbourg, 4 rue Blaise Pascal, 67070 Strasbourg, France

Abstract

A copper-catalysed three-component coupling reaction between a carbonyl derivative, a terminal ynamide and an amine has been developed for the one-pot construction of γ-amino-ynamides under mild and environmentally-friendly conditions.

Funder

Centre National de la Recherche Scientifique

Université de Strasbourg

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D2GC00966H

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