Asymmetric addition of α-branched cyclic ketones to allenamides catalyzed by a chiral phosphoric acid-Reference-Cited by-同舟云学术

Asymmetric addition of α-branched cyclic ketones to allenamides catalyzed by a chiral phosphoric acid

Published:2016 Issue:4 Volume:7 Page:2653-2656
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yang Xiaoyu¹²³⁴,Toste F. Dean¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of California

3. Berkeley

4. USA

Abstract

Asymmetric addition of unactivated α-branched cyclic ketones to allenamides catalyzed by a chiral phosphoric acid catalyst, generates an all-carbon quaternary stereocenter with broad substrate scope and high enantioselectivity.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC04202J

Reference57 articles.

1. Asymmetric Catalysis Special Feature Part I: Catalytic asymmetric synthesis of all-carbon quaternary stereocenters

2. Stereoselective Construction of Quaternary Stereocenters

3. Catalytic Enantioselective Construction of All-Carbon Quaternary Stereocenters

4. Organocatalytic Formation of Quaternary Stereocenters

5. Enantioselective synthesis of all-carbon quaternary stereogenic centers in acyclic systems

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