Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones-Reference-Cited by-同舟云学术

Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones

Published:2017 Issue:3 Volume:8 Page:559-570
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Goud Gudikadi Linga¹²³⁴⁵,Ramesh Seela¹²³⁴⁵,Ashok Dongamanti¹²³⁴⁵^ORCID,Reddy Vummenthala Prabhakar¹²³⁴⁵,Yogeeswari Perumal⁶⁷⁴⁵,Sriram Dharmarajan⁶⁷⁴⁵,Saikrishna Balabadra⁸²³⁴⁵,Manga Vijjulatha⁸²³⁴⁵

Affiliation:

1. Green and Medicinal Chemistry Laboratory

2. Department of Chemistry

3. Osmania University

4. Hyderabad

5. India

6. Department of Pharmacy

7. Birla Institute of Technology & Science - Hyderabad Campus

8. Molecular Modeling and Medicinal Chemistry Group

Abstract

As part of an ongoing effort to develop new antitubercular and antimicrobial agents, a series of substituted xanthenone derivatives (7a–p) were synthesized.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C6MD00593D

Reference45 articles.

1. World Health Organization , Global Tuberculosis Report, 2015

2. Tetraoxygenated naturally occurring xanthones

3. Total synthesis of psorospermin

4. Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells

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