New chalcone derivatives: synthesis, antiviral activity and mechanism of action-Reference-Cited by-同舟云学术

New chalcone derivatives: synthesis, antiviral activity and mechanism of action

Published:2020 Issue:41 Volume:10 Page:24483-24490
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Fu Yun¹²³⁴⁵,Liu Dan¹²³⁴⁵,Zeng Huanan¹²³⁴⁵,Ren Xiaoli¹²³⁴⁵,Song Baoan¹²³⁴⁵^ORCID,Hu Deyu¹²³⁴⁵,Gan Xiuhai¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering

2. Key Laboratory of Green Pesticide and Agricultural Bioengineering

3. Ministry of Education

4. Center for Research and Development of Fine Chemicals

5. Guizhou University

Abstract

The chalcone derivatives containing a purine (sulfur) ether moiety were synthesized. The antiviral mechanism suggested that the antiviral activity of compound 5d may depend on its stronger binding affinity with TMV-CP.

Funder

National Natural Science Foundation of China

Department of Education of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA03684F

Reference33 articles.

1. 100 years of virology: from vitalism via molecular biology to genetic engineering

2. Design, Synthesis, and Anti-tobacco Mosaic Virus (TMV) Activity of Phenanthroindolizidines and Their Analogues

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4. Natural products, their derivatives, mimics and synthetic equivalents: role in agrochemical discovery

5. Chalcone derivatives bearing chromen or benzo[f]chromen moieties: Design, synthesis, and evaluations of anti-inflammatory, analgesic, selective COX-2 inhibitory activities

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