Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(ii) bis(thiosemicarbazone) complexes-Reference-Cited by-同舟云学术

Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(ii) bis(thiosemicarbazone) complexes

Published:2015 Issue:57 Volume:5 Page:46031-46049
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Haribabu Jebiti¹²³⁴,Jeyalakshmi Kumaramangalam¹²³⁴,Arun Yuvaraj⁵⁶⁷⁴,Bhuvanesh Nattamai S. P.¹⁸⁹¹⁰,Perumal Paramasivan Thirumalai⁵⁶⁷⁴,Karvembu Ramasamy¹²³⁴

Affiliation:

1. Department of Chemistry

2. National Institute of Technology

3. Tiruchirappalli-620015

4. India

5. Organic Chemistry Division

6. CSIR-Central Leather Research Institute

7. Chennai-600020

8. Texas A & M University

9. College Station

10. USA

Abstract

Cytotoxic nickel(ii) complexes with an N-substituted isatin thiosemicarbazone were synthesized and their interaction with CT DNA and BSA protein was investigated, which was supported by molecular docking studies.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA04498G

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