A one-pot five component reaction for the synthesis of tetrazol-benzofuran hybrids and their inhibitory activity against <i>Mucor lusitanicus</i>-Reference-Cited by-同舟云学术

A one-pot five component reaction for the synthesis of tetrazol-benzofuran hybrids and their inhibitory activity against Mucor lusitanicus

Published:2024 Issue:35 Volume:22 Page:7240-7244
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Aguilar-Morales Cesia M.¹,Alejandre-Castañeda Viridiana²,Contreras-Celedón Claudia¹,Ramírez-Díaz Martha Isela²,Islas-Jácome Alejandro³,Meza-Carmen Victor²,Chacón-García Luis¹^ORCID,Cortés-García Carlos J.¹^ORCID

Affiliation:

1. Laboratorio de Diseño Molecular, Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, C.P. 58030, Morelia, Michoacán, Mexico

2. Laboratorio de Diferenciación Celular, Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ed. B-1, Ciudad Universitaria, Morelia, Michoacán 58030, Mexico

3. Departamento de Química, Universidad Autónoma Metropolitana-Iztapalapa, Av. Ferrocarril San Rafael Atlixco 186, Col. Leyes de Reforma 1A Sección, Iztapalapa, Ciudad de México, 09310, Mexico

Abstract

The synthesis of a novel 1,5-disubstituted tetrazole-benzofuran hybrid system by a high-order multicomponent reaction with promising antifungal activity against mucormycosis is reported.

Funder

Coordinación de la Investigación Científica

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00995A

Reference24 articles.

1. Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design

2. Synthesis of polyheterocyclesviamulticomponent reactions

3. Chemistry and Biology Of Multicomponent Reactions

4. Recent applications of multicomponent reactions in medicinal chemistry

5. Tetrazoles via Multicomponent Reactions