Synthesis and functional evaluation of proteinogenic amino acid-derived synthetic cannabinoid receptor agonists related to MPP-5F-PICA, MMB-5F-PICA, and MDMB-5F-PICA

Author:

Sparkes Eric12ORCID,Markham Jack W.123ORCID,Boyd Rochelle13,Udoh Michael13,Gordon Rebecca13ORCID,Zaman Humayra4,Walker Katelyn A.15,Dane Chianna2,Kevin Richard C.167ORCID,Santiago Marina J.4ORCID,Hibbs David E.3ORCID,Banister Samuel D.12ORCID,Ametovski Adam12,Cairns Elizabeth A.13ORCID

Affiliation:

1. Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, The University of Sydney, 94 Mallett St, Building M02F, Camperdown, Sydney, NSW 2050, Australia

2. School of Chemistry, Faculty of Science, The University of Sydney, NSW 2050, Australia

3. Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, NSW 2050, Australia

4. Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW 2109, Australia

5. School of Psychology, Faculty of Science, The University of Sydney, NSW 2050, Australia

6. Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital Sydney, Sydney, NSW 2010, Australia

7. School of Clinical Medicine, The University of New South Wales, Sydney, NSW 2052, Australia

Abstract

α-Amino acid derived synthetic cannabinoid receptor agonists.

Funder

University of Sydney

Publisher

Royal Society of Chemistry (RSC)

Reference41 articles.

1. European Monitoring Centre for Drugs and Drug Addiction, European Drug Report 2023, 2023

2. UNODC , World Drug Report 2023, United Nations , 2023

3. Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol

4. S. D.Banister and M.Connor , The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins , Handb. Exp. Pharmacol. , 2018 , vol. 252 , pp. 165–190

5. S. D.Banister and M.Connor , The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution, Handb. Exp. Pharmacol. , 2018 , vol. 252 , pp. 191–226

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