Cues from human atrial extracellular matrix enrich the atrial differentiation of human induced pluripotent stem cell-derived cardiomyocytes-Reference-Cited by-同舟云学术

Cues from human atrial extracellular matrix enrich the atrial differentiation of human induced pluripotent stem cell-derived cardiomyocytes

Published:2021 Issue:10 Volume:9 Page:3737-3749
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Mesquita Fernanda C. P.¹²³,Morrissey Jacquelynn¹²³,Lee Po-Feng¹²³,Monnerat Gustavo⁴⁵⁶⁷,Xi Yutao¹²³,Andersson Helen¹²³,Nogueira Fabio C. S.⁴⁵⁶⁷^ORCID,Domont Gilberto B.⁴⁵⁶⁷,Sampaio Luiz C.¹²³⁸⁹,Hochman-Mendez Camila¹²³^ORCID,Taylor Doris A.¹²³¹⁰²

Affiliation:

1. Texas Heart Institute

2. Houston

3. USA

4. Institute of Chemistry

5. Federal University of Rio de Janeiro

6. Rio de Janeiro

7. Brazil

8. Michael E. DeBakey Department of Surgery

9. Baylor College of Medicine

10. RegenMedix Consulting LLC

Abstract

Decellularized extracellular matrix (dECM) from human atria preserves key native components that directed the cardiac differentiation of hiPSCs to an atrial-like phenotype, yielding a twofold increase of functional atrial-like cells.

Funder

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Houston Endowment

Texas Emerging Technology Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM01686A