A novel surfactant aided micellar system of oxidation inhibitors in clotrimazole bioadhesive gel: development, characterization, in vitro and in vivo antifungal evaluation against Candida clinical isolates

Author:

Bhardwaj Varun1234,Monga Jitender567,Sharma Amit867,Sharma Shailesh91011,Sharma Arun1234,Sharma Poonam1234

Affiliation:

1. Department of Biotechnology

2. Bioinformatics and Pharmacy

3. Jaypee University of Information Technology

4. , India

5. Department of Medical Urology

6. Postgraduate Institute of Medical Education and Research (PGIMER)

7. Chandigarh, India

8. Department of Medical Parasitology

9. Department of Pharmaceutics

10. ASBASJSM College of Pharmacy

11. Ropar, India

Abstract

Clotrimazole (CLZ) is a widely used antifungal agent with poor aqueous solubility, which requires the development of new delivery systems to improve its therapeutic activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference43 articles.

1. The search for the fungal tree of life

2. R. G. Dalziel , J. R.Fitzgerald, C. A.Mims, A. A.Nash and J.Stephen, Mims' pathogenesis of infectious disease, Academic Press, 2000

3. Epidemiology of Nosocomial Fungal Infections, with Emphasis on Candida Species

4. Epidemiology of superficial fungal infections

5. Candida albicans, a major human fungal pathogen

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