Synthesis of C11-to-C14 methyl-shifted all-trans-retinal analogues and their activities on human aldo-keto reductases-Reference-Cited by-同舟云学术

Synthesis of C11-to-C14 methyl-shifted all-trans-retinal analogues and their activities on human aldo-keto reductases

Published:2020 Issue:25 Volume:18 Page:4788-4801
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Rivas Aurea¹²³⁴⁵,Pequerul Raquel⁶⁷⁸⁹¹⁰,Barracco Vito⁶⁷⁸⁹¹⁰,Domínguez Marta¹²³⁴⁵,López Susana¹²¹¹¹²¹⁰,Jiménez Rafael⁶⁷⁸⁹¹⁰,Parés Xavier⁶⁷⁸⁹¹⁰,Alvarez Rosana¹²³⁴⁵^ORCID,Farrés Jaume⁶⁷⁸⁹¹⁰,de Lera Angel R.¹²³⁴⁵^ORCID

Affiliation:

1. Departamento de Química Orgánica

2. Facultade de Química

3. CINBIO and IIS Galicia Sur

4. Universidade de Vigo

5. E-36310 Vigo

6. Department of Biochemistry and Molecular Biology

7. Faculty of Biosciences

8. Universitat Autònoma de Barcelona

9. E-08193 Bellaterra

10. Spain

11. Universidade de Santiago de Compostela

12. E-15782 Santiago

Abstract

Human aldo-keto reductases (AKRs) are enzymes involved in the reduction, among other substrates, of all-trans-retinal to all-trans-retinol (vitamin A), thus contributing to the control of the levels of retinoids in organisms.

Funder

Ministerio de Economía y Competitividad

Xunta de Galicia

Regione Toscana

Universitat Autònoma de Barcelona

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01084G

Reference77 articles.

1. Retinoic acid in development: towards an integrated view

2. Retinoic Acid Synthesis and Signaling during Early Organogenesis

3. Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids

4. G Protein–Coupled Receptor Rhodopsin

5. A G protein-coupled receptor at work: the rhodopsin model

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