A dearomative ipso-iodocyclization/desymmetrization sequence leading to optically active tricyclic piperazine scaffolds-Reference-Cited by-同舟云学术

A dearomative ipso-iodocyclization/desymmetrization sequence leading to optically active tricyclic piperazine scaffolds

Published:2020 Issue:18 Volume:18 Page:3501-3511
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Okitsu Takashi¹²³^ORCID,Horike Arisa¹²³,Shimazawa Natsumi¹²³,Wada Akimori¹²³

Affiliation:

1. Kobe Pharmaceutical University

2. Kobe 658-8558

3. Japan

Abstract

A dearomative ipso-iodocyclization/desymmetrization sequence enabled the transformation from highly planar aromatic substrates to optically active tricyclic piperazine scaffolds.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00510J

Reference51 articles.

1. Dearomatization Strategies in the Synthesis of Complex Natural Products

2. ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones

3. Dearomatization through Halofunctionalization Reactions

4. Recent advances in chemical dearomatization of nonactivated arenes

5. Selective Arene Hydrogenation for Direct Access to Saturated Carbo‐ and Heterocycles

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