Identification of novel pyrazole–rhodanine hybrid scaffolds as potent inhibitors of aldose reductase: design, synthesis, biological evaluation and molecular docking analysis-Reference-Cited by-同舟云学术

Identification of novel pyrazole–rhodanine hybrid scaffolds as potent inhibitors of aldose reductase: design, synthesis, biological evaluation and molecular docking analysis

Published:2016 Issue:81 Volume:6 Page:77688-77700
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Andleeb Hina¹²³⁴,Tehseen Yildiz⁵⁶⁷⁴,Ali Shah Syed Jawad⁵⁶⁷⁴,Khan Imtiaz¹²³⁴,Iqbal Jamshed⁵⁶⁷⁴,Hameed Shahid¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Quaid-i-Azam University

3. Islamabad-45320

4. Pakistan

5. Centre for Advanced Drug Research

6. COMSATS Institute of Information Technology

7. Abbottabad-22060

Abstract

A series of novel pyrazole–rhodanine derivatives was designed, synthesized, and biologically evaluated for their potential inhibitory effect on both aldehyde reductase (ALR1) and aldose reductase (ALR2).

Funder

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA14531K

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