Self-assembly of diclofenac prodrug into nanomicelles for enhancing the anti-inflammatory activity

Author:

Assali Mohyeddin12345ORCID,Shawahna Ramzi62345,Alhawareen Raeda12345,Najajreh Haifa12345,Rabaya Oraib12345,Faroun Maryam7895,Zyoud Ahed1011345ORCID,Hilal Hikmat1011345

Affiliation:

1. Department of Pharmacy

2. Faculty of Medicine and Health Sciences

3. An-Najah National University

4. Nablus

5. Palestine

6. Department of Physiology, Pharmacology, and Toxicology

7. The Nanotechnology Research Laboratory

8. Materials Engineering Department

9. Al-Quds University

10. Department of Chemistry

11. Faculty of Science

Abstract

Amphiphilic diclofenac prodrugs were successfully synthesized and self-assembled into the nano-micellar structures that have improved the anti-inflammatory activity in vivo.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference36 articles.

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