Synthesis, structural studies and biological properties of some phosphono-perfluorophenylalanine derivatives formed by SNAr reactions-Reference-Cited by-同舟云学术

Synthesis, structural studies and biological properties of some phosphono-perfluorophenylalanine derivatives formed by SNAr reactions

Published:2019 Issue:42 Volume:9 Page:24117-24133
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kwiczak-Yiğitbaşı Joanna¹²³⁴⁵,Pirat Jean-Luc⁵⁶⁷⁸⁹,Virieux David⁵⁶⁷⁸⁹^ORCID,Volle Jean-Noël⁵⁶⁷⁸⁹,Janiak Agnieszka¹²³⁴^ORCID,Hoffmann Marcin¹²³⁴^ORCID,Mrzygłód Jakub¹²³⁴,Wawrzyniak Dariusz¹⁰¹¹¹²⁴,Barciszewski Jan¹⁰¹¹¹²⁴¹³^ORCID,Pluskota-Karwatka Donata¹²³⁴^ORCID

Affiliation:

1. Adam Mickiewicz University in Poznań

2. Faculty of Chemistry

3. 61-614 Poznań

4. Poland

5. AM2N

6. UMR 5253

7. ICGM

8. ENSCM

9. 34296 Montpellier Cedex 5

10. Institute of Bioorganic Chemistry

11. Polish Academy of Sciences

12. 61-704 Poznań

13. NanoBioMedical Center of Adam Mickiewicz University

Abstract

Several novel phosphono-perfluorophenylalanine derivatives, as mimetics of phenylalanine, were synthesized by subjecting diethyl (2-(perfluorophenyl)-1-(phenylamino)ethyl)-phosphonate to S_NAr reactions with thiols, amines and phenols.

Funder

Infrastruktura PL-Grid

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA03982A

Reference66 articles.

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4. Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry

5. Synthesis and antitumor activities of novel thiourea α-aminophosphonates from dehydroabietic acid

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