Transition-metal-free direct nucleophilic substitution of carboranyllithium and 2-halopyridines-Reference-Cited by-同舟云学术

Transition-metal-free direct nucleophilic substitution of carboranyllithium and 2-halopyridines

Published:2019 Issue:32 Volume:17 Page:7438-7441
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lu Ju-You¹²³⁴⁵^ORCID,Zhao Bo⁶⁷⁸⁹,Du Yongmei⁶⁷⁸⁹,Yang Jianxin¹²³⁴⁵,Lu Jian⁶⁷⁸⁹

Affiliation:

1. Laboratory of Green Catalysis and Reaction Engineering of Haikou

2. Hainan Provincial Fine Chemical Engineering Research Center

3. School of Sciences

4. Hainan University

5. Haikou 570228

6. State Key Laboratory of Fluorine & Nitrogen Chemicals

7. Xi'an Modern Chemistry Research Institute

8. Xi'an

9. China

Abstract

An efficient C(cage)–heteroarylation of carborane is presented, via direct nucleophilic substitution of carboranyllithium with 2-halopyridines under transition-metal-free conditions. The process utilizes readily available carboranyllithium nucleophile, and exhibits a broad substrate scope.

Funder

Hainan University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00978G

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1. Dicarba-closo-dodecaboranes C2B10H12 and their derivatives

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