New and sensitive HPLC-UV method for concomitant quantification of a combination of antifilariasis drugs in rat plasma and organs after simultaneous oral administration-Reference-Cited by-同舟云学术

New and sensitive HPLC-UV method for concomitant quantification of a combination of antifilariasis drugs in rat plasma and organs after simultaneous oral administration

Published:2021 Issue:7 Volume:13 Page:933-945
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Permana Andi Dian¹²³⁴⁵^ORCID,Wahyudin Elly⁶²³⁴⁵,Ismail ⁷²³⁴⁵,Amir Muh. Nur⁶²³⁴⁵,Raihan Muh.⁷²³⁴⁵,Anjani Qonita Kurnia⁸⁹¹⁰¹¹,Utomo Emilia⁸⁹¹⁰¹¹,Layadi Patricia¹²³⁴⁵,Donnelly Ryan F.⁸⁹¹⁰¹¹

Affiliation:

1. Department of Pharmaceutics

2. Faculty of Pharmacy

3. Hasanuddin University

4. Makassar

5. Indonesia

6. Department of Pharmacology-Toxicology

7. Department of Phytochemistry

8. School of Pharmacy

9. Queen's University Belfast

10. Belfast

11. UK

Abstract

A sensitive HPLC-UV method for simultaneous analysis of the drugs used in lymphatic filariasis treatment, namely IVM, ABZ and DOX has been validated. The method was applied in pharmacokinetic and biodistribution studies in Wistar rats.

Funder

Universitas Hasanuddin

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D0AY02258F

Reference37 articles.

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4. WHO , Global programme to eliminate lymphatic filariasis: progress report , 2017–2018

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