Ecological HPLC method for analyzing an antidiabetic drug in real rat plasma samples and studying the effects of concurrently administered fenugreek extract on its pharmacokinetics

Author:

Abdelwahab Nada S.12345ORCID,Morsi Amani6785,Ahmed Yasmine M.92345,Hassan Hossam M.1021145ORCID,AboulMagd Asmaa M.12345ORCID

Affiliation:

1. Pharmaceutical Chemistry Department

2. Faculty of Pharmacy

3. Nahda University (NUB)

4. Beni-Suef

5. Egypt

6. Analytical Chemistry Department

7. National Organization of Drug Control and Research (NODCAR)

8. Giza

9. Pharmacology & Toxicology Department

10. Pharmacognosy Department

11. Beni-Suef University

Abstract

The combination of fenugreek extract and metformin can be considered as an auspicious treatment for satisfactory diabetes control and minimizing the expected long-term complications of metformin.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference54 articles.

1. Insulin action enhancers for the management of Type 2 diabetes mellitus

2. T. L.Lemke , D. A.Williams , V. F.Roche and S. W.Zito , Foye's Principles of Medicinal Chemistry , Lippincott Williams & Wilkins , 6 th edn, 2008 , p. 855

3. Validation of an HPLC-UV Method for the determination of metformin hydrochloride in spiked-Human plasma for the application of therapeutic drug monitoring

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