Ru(<scp>ii</scp>)arene(N^N bpy/phen)-based RAPTA complexes for <i>in vitro</i> anti-tumour activity in human glioblastoma cancer cell lines and <i>in vivo</i> toxicity studies in a zebrafish model-Reference-Cited by-同舟云学术

Ru(ii)arene(N^N bpy/phen)-based RAPTA complexes for in vitro anti-tumour activity in human glioblastoma cancer cell lines and in vivo toxicity studies in a zebrafish model

Published:2022 Issue:29 Volume:12 Page:18911-18922
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

P. K. Anuja¹,Kar Binoy¹^ORCID,Roy Nilmadhab¹^ORCID,Paira Priyankar¹^ORCID

Affiliation:

1. Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore-632014, Tamilnadu, India

Abstract

A series of half-sandwich Ru(ii)arene(N^N bpy/phen)-based RAPTA complexes have been developed for brain cancer therapy.

Funder

Science and Engineering Research Board

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02677E

Reference33 articles.

1. Bioorganometallic chemistry—from teaching paradigms to medicinal applications

2. Metal-based Drugs

3. DNA and its associated processes as targets for cancer therapy

4. Glioblastoma: From Molecular Pathology to Targeted Treatment

5. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New Ru(II)-p-cymene compounds bearing indomethacin and indomethacin-pyridineamide ligands: synthesis, characterization, computational studies and investigation of their interactions with the Human Serum Albumin;Inorganica Chimica Acta;2024-07

2. Synthesis of novel rapanone derivatives via organocatalytic reductive C-alkylation: biological evaluation of antioxidant properties, in vivo zebrafish embryo toxicity, and docking studies;RSC Medicinal Chemistry;2024

3. First 4,7-oxygenated 1,10-phenanthroline-2,9-diamides: synthesis, tautomerism and complexation with REE nitrates;Dalton Transactions;2024

4. Design of an anticancer organoruthenium complex as the guest and polydiacetylene-coated fluorogenic nanocarrier as the host: engineering nanocarrier using ene-yne conjugation for sustained guest release, enhanced anticancer activity and reduced in vivo toxicity;Dalton Transactions;2024

5. Exploring the phototoxicity of GSH-resistant 2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)quinoline-based Ir(iii)-PTA complexes in MDA-MB-231 cancer cells;Dalton Transactions;2024