Design, synthesis, and anticancer activities of new compounds bearing the quinone–pyran–lactone tricyclic pharmacophore-Reference-Cited by-同舟云学术

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Design, synthesis, and anticancer activities of new compounds bearing the quinone–pyran–lactone tricyclic pharmacophore

Published:2015 Issue:35 Volume:5 Page:27502-27508
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jiang Xue¹²³⁴,Wang Meining⁵⁶⁷⁸⁹,Song Shanshan¹⁰⁷⁸⁹⁴,Xu Youjun¹²³⁴,Miao Zehong¹⁰⁷⁸⁹⁴,Zhang Ao⁵⁶⁷⁸⁹

Affiliation:

1. School of Pharmaceutical Engineering

2. Shenyang Pharmaceutical University

3. Shenyang 110016

4. China

5. CAS Key Laboratory of Receptor Research

6. Synthetic Organic & Medicinal Chemistry Laboratory (SOMCL)

7. Shanghai Institute of Materia Medica (SIMM)

8. Chinese Academy of Sciences

9. Shanghai 201203

10. State Key Laboratory of Drug Research

Abstract

A simple and effective synthesis of the tricyclic quinone–pyran–lactone skeleton was developed and subsequent structural modification was conducted.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA00154D

Reference27 articles.

1. Pyranonaphthoquinone antibiotics—isolation, structure and biological activity

2. Pyranonaphthoquinones—isolation, biological activity and synthesis

3. Synthetic Strategies Towards Pyranonaphthoquinone Antibiotics

4. Isolation of cytotoxic substance, kalafungin from an alkalophilic actinomycete, Nocardiopsis dassonvillei subsp. prasina.

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