A comparative review of computational methods for pathway perturbation analysis: dynamical and topological perspectives-Reference-Cited by-同舟云学术

A comparative review of computational methods for pathway perturbation analysis: dynamical and topological perspectives

Published:2017 Issue:9 Volume:13 Page:1692-1704
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Vanhaelen Q.¹²³⁴^ORCID,Aliper A. M.¹²³⁴,Zhavoronkov A.¹²³⁴

Affiliation:

1. Insilico Medicine Inc.

2. Johns Hopkins University

3. ETC

4. USA

Abstract

Stem cells offer great promise within the field of regenerative medicine but despite encouraging results, the large scale use of stem cells for therapeutic applications still faces challenges when it comes to controlling signaling pathway responses with respect to environmental perturbations.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MB/C7MB00170C

Reference83 articles.

1. A brief definition of regenerative medicine

2. Potential for pharmacological manipulation of human embryonic stem cells

3. Pluripotent stem cells in disease modelling and drug discovery

4. Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers

5. Prediction and Testing of Novel Transcriptional Networks Regulating Embryonic Stem Cell Self-Renewal and Commitment

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transcriptome-Wide Profile of 25-Hydroxyvitamin D3 in Primary Immune Cells from Human Peripheral Blood;Nutrients;2021-11-16

2. CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy;Cell Systems;2021-02

3. Integrated machine learning framework for computer-aided chemical product design;Applications of Artificial Intelligence in Process Systems Engineering;2021

4. Common and personal target genes of the micronutrient vitamin D in primary immune cells from human peripheral blood;Scientific Reports;2020-12

5. Diverse Cell Stimulation Kinetics Identify Predictive Signal Transduction Models;iScience;2020-10