Novel naphthoquinone derivatives and evaluation of their trypanocidal and leishmanicidal activities-Reference-Cited by-同舟云学术

Novel naphthoquinone derivatives and evaluation of their trypanocidal and leishmanicidal activities

Published:2015 Issue:2 Volume:13 Page:428-437
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Naujorks Aline Alves dos Santos¹²³⁴⁵,da Silva Adriano Olímpio⁶³⁴⁵,Lopes Rosangela da Silva⁶³⁴⁵,de Albuquerque Sérgio⁷⁸⁹¹⁰¹¹,Beatriz Adilson⁶³⁴⁵,Marques Maria Rita²¹²³⁴⁵,de Lima Dênis Pires⁶³⁴⁵

Affiliation:

1. Programa de Pós-Graduação em Farmácia

2. Centro de Ciências Biológicas e da Saúde

3. Universidade Federal de Mato Grosso do Sul

4. Campo Grande

5. Brazil

6. Instituto de Química (LP4)

7. Departamento de Análises Clínicas

8. Toxicológicas e Bromatológicas

9. Faculdade de Ciências Farmacêuticas de Ribeirão Preto

10. USP

11. Ribeirão Preto

12. Laboratório de Bioquímica

Abstract

Novel naphthoquinone derivatives were synthesized and tested for trypanocidal and leishmanicidal activities. Compound 11a was the most active against T. cruzi.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB01869A

Reference40 articles.

1. WHO. World Health Organization. Neglected Tropical Diseases. Chagas disease (American trypanosomiasis). Media Centre. Fact sheet n° 340. 2012. http://www.who.int/mediacentre/factsheets/fs340/en/

2. Trypanosoma cruzi: Activities of lapachol and α- and β-lapachone derivatives against epimastigote and trypomastigote forms

3. Chagas Disease

4. Epidemiology of Chagas disease in non endemic countries: the role of international migration

5. L. V. Kirchhoff , in Harrison Medicina Interna, ed. E. Braunwald, A. S. Fauci, D. L. Kasper, S. L. Hauser, D. L. Longo and J. R. Jameson, McGrawHill, Rio de Janeiro, 15th edn, 2002, vol. 1, ch. 216, pp. 1290–1292

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