A facile and highly chemoselective synthesis of 1-thia-3a,6-diaza-benzo[e]azulen-3-ones by 7-exo-dig/trig halocyclizations-Reference-Cited by-同舟云学术

A facile and highly chemoselective synthesis of 1-thia-3a,6-diaza-benzo[e]azulen-3-ones by 7-exo-dig/trig halocyclizations

Published:2016 Issue:103 Volume:6 Page:101587-101591
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kuila Bilash¹²³⁴,Mahajan Dinesh⁵⁶⁷⁴,Singh Prabhpreet⁸⁹¹⁰⁴,Bhargava Gaurav¹²³⁴

Affiliation:

1. Department of Chemical Sciences

2. I. K. Gujral Punjab Technical University

3. Kapurthala

4. India

5. Drug Discovery Research Centre (DDRC)

6. Translational Health Sciences and Technology Institute (THSTI)

7. Faridabad-121001

8. Department of Chemistry

9. Guru Nanak Dev University

10. Amritsar

Abstract

The manuscript describes a study on relatively unexplored halogen mediated 7-exo-dig/trig cyclization reactions of 2-(2-amino-aryl)-3-prop-2-ynyl/allyl-thiazolidin-4-ones for the formation of thiazole condensed 1,4-benzodiazepines in good yields.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA23493C

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5. Synthesis of 2,4,5-Trisubstituted 3-Fluorofurans via Sequential Iodocyclization and Cross-Coupling of gem-Difluorohomopropargyl Alcohols

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