Mononuclear copper(i) complexes of triphenylphosphine and N,N′-disubstituted thioureas as potential DNA binding chemotherapeutics

Author:

Khan Syed Ishtiaq12345,Ahmad Sajjad67849,Khan Inayat Ali67849,Badshah Amin1234,Rauf Muhammad Khawar1234,Putejo Jahangir Ali1234ORCID,Siddiq Muhammad Nasir5101112,Kausar Samia113144,Altaf Ataf Ali115164ORCID

Affiliation:

1. Department of Chemistry

2. Quaid-i-Azam University

3. Islamabad 45320

4. Pakistan

5. Chemistry of Interfaces

6. Department of Health and Biological Sciences

7. Abasyn University

8. Peshawar 25000

9. Geoscience Advance Research Laboratories

10. Luleå University of Technology

11. SE-97187 Luleå

12. Sweden

13. University of Gujrat

14. Gujrat 50700

15. University of Okara

16. Okara-56300

Abstract

Herein, nine copper(i) bromide complexes with N,N′-disubstituted thioureas and triphenylphosphine, were synthesized via a simple solution-based reaction at 60 °C and characterized, selected complexes were screened for DNA binding.

Funder

Higher Education Commission, Pakistan

Université de Montréal

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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