Blocking CD47 with restructured peptide nanoparticles for motivating phagocytosis to inhibit tumor progression-Reference-Cited by-同舟云学术

Blocking CD47 with restructured peptide nanoparticles for motivating phagocytosis to inhibit tumor progression

Published:2022 Issue:15 Volume:10 Page:4324-4334
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Xia Yiyi¹^ORCID,Wang Tiantian²^ORCID,Wu Linjie¹,Zhong Haiqing¹,Zhou Yi¹,Ke Peng¹,Bao Xiaoyan¹,Dai Qi¹³,Yang Qiyao¹³,Lu Yiying¹,Xu Donghang²,Liang Min⁴,Han Min¹^ORCID

Affiliation:

1. Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

2. Department of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China

3. Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310058, China

4. Department of Anesthesiology, Anesthesiology Research Institute, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China

Abstract

Hypoxia-responsive peptide nanoparticles self-assemble to form nanofiber networks to block CD47 and further enhance anti-tumor immune response in combination with chemotherapy.

Funder

National Key Research and Development Program of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00189F

Reference25 articles.

1. Overcoming malignant cell-based mechanisms of resistance to immune checkpoint blockade antibodies

2. Identification and Utilization of Biomarkers to Predict Response to Immune Checkpoint Inhibitors

3. Phagocytosis checkpoints as new targets for cancer immunotherapy

4. CD47: role in the immune system and application to cancer therapy

5. Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis

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