Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation-Reference-Cited by-同舟云学术

Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation

Published:2022 Issue:12 Volume:10 Page:3029-3053
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Mills Jessica A.¹²³^ORCID,Liu Feifei¹²³⁴^ORCID,Jarrett Thomas R.¹²³⁴^ORCID,Fletcher Nicholas L.¹²³^ORCID,Thurecht Kristofer J.¹²³⁴^ORCID

Affiliation:

1. Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia

2. Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD 4072, Australia

3. ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Australia

4. ARC Centre for Innovation in Biomedical Imaging Technology, Australia

Abstract

Nanomedicine recognition and clearance by the mononuclear phagocyte system (MPS) impedes optimal clinical impacts for this class of materials. We present an overview of factors involved in MPS interactions and approaches to overcome this barrier.

Funder

National Health and Medical Research Council

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00181K

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